Clinical trial for Clinical High Risk for Psychosis (CHR)
Official title Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis
ClinicalTrials.gov ID: NCT07786714
What this study is testing
- What it's testing
- This study checks if a fast form of brain stimulation is safe and if it helps with depression. It also looks for signs that show if the treatment works.
- Who it's for
- Young people who are at high risk of developing psychosis.
- What's involved
- Participants get brain stimulation or a fake version for five days in a row. They also do brain tests, wear a Fitbit, and use phone apps to track their health.
- Time commitment
- The study lasts about 3 months, with visits one week, one month, and three months after the treatment ends.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 34
You may be able to join if
- Meets clinical CHR-P criteria, confirmed by the Structured Interview for Psychosis-Risk Syndromes (SIPS)
- Clinical team confirms sufficient stability to participate
- Able to provide informed consent
You likely can't join if
- Pregnancy, lactation, or intrauterine device
- History of electroconvulsive therapy (ECT) in the past 6 months
- Substance use during the treatment week (cigarettes and cannabis excluded from this consideration)
- Contraindications for TMS (e.g., metal implants in head/neck, seizure history, brain tumor/neurosurgery, severe cardiac disease)
- Previous rTMS treatment
- Documented history of significant intellectual disability
The study team makes the final eligibility decision.
Where it is enrolling
- Verdun, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 34 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Verdun, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.