Clinical trial for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Official title Effects of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives
ClinicalTrials.gov ID: NCT07792408
What this study is testing
What is VX-407?
an investigational oral tablet being studied as a potential treatment for autosomal dominant polycystic kidney disease (ADPKD)
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study checks if the new medicine changes how birth control pills work in the body and if it is safe to take them together.
- Who it's for
- Healthy adults who currently use combined oral contraceptives.
- What's involved
- Participants will take the new medicine and birth control pills, then have blood tests to measure drug levels.
- Time commitment
- The study involves short-term visits for blood tests and monitoring.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50, women only. Healthy volunteers may be eligible.
You may be able to join if
- Body mass index (BMI) of 18.0 to 30.0 kilogram per meter square (kg/m\^2), inclusive
- A total body weight of greater than (\>) 50 kg Key
You likely can't join if
- History of febrile illness within 5 days before the first dose of study drug
- Pregnant, nursing, or planning to become pregnant during the study or within 90 days after the last dose of study drug Other protocol defined...
The study team makes the final eligibility decision.
Where it is enrolling
- Montreal, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montreal, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.