Dry Eye study: Lacrifill vs Saline
Official title Evaluation of Lacrifill
ClinicalTrials.gov ID: NCT07796178
What this study is testing
What is Lacrifill?
An investigational intracanalicular occlusion device being studied for preventing post‑operative dry eye symptoms after cataract surgery.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see if Lacrifill can reduce dry eye symptoms that sometimes happen after cataract surgery.
- Who it's for
- Adults who recently had cataract surgery on one eye and may develop dry eye.
- What's involved
- Participants will receive Lacrifill and may have eye exams and tests to check tear function and eye comfort.
- Time commitment
- The study lasts a few weeks after surgery, with a few follow‑up visits to monitor eye health.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Adults ≥18 years of age.
- Have the potential of 20/40 visual acuity or better post-cataract surgery.
- have cataract surgery scheduled for both eyes
- Corneal staining score of ≥3 on the original National Eye Institute (NEI; 0-15 total score) staining scale in the study eye.
- willing to discontinue contact lens throughout the study?
You likely can't join if
- Known systemic health conditions that are known to alter tear film physiology (e.g., primary and secondary Sjögren's syndrome)?
- History of ocular surgery within the past 12 months (excluding cataract surgery)
- Anticipated complications from cataract surgery in either eye?
- History of severe ocular trauma, active ocular infection or inflammation that is not dry eye-related?
- Used Accutane or is currently using ocular medications/treatments outside of study treatments? Artificial tears will be allowed.
- Physical meibomian gland treatment withing 1 month of enrollment?
See the full eligibility criteria
- Adults ≥18 years of age.
- Have the potential of 20/40 visual acuity or better post-cataract surgery.
- have cataract surgery scheduled for both eyes
- Corneal staining score of ≥3 on the original National Eye Institute (NEI; 0-15 total score) staining scale in the study eye.
- willing to discontinue contact lens throughout the study?
- pre-treatment OSDI scores of ≤12 (asymptomatic)?
- Known systemic health conditions that are known to alter tear film physiology (e.g., primary and secondary Sjögren's syndrome)?
- History of ocular surgery within the past 12 months (excluding cataract surgery)
- Anticipated complications from cataract surgery in either eye?
- History of severe ocular trauma, active ocular infection or inflammation that is not dry eye-related?
- Used Accutane or is currently using ocular medications/treatments outside of study treatments? Artificial tears will be allowed.
- Physical meibomian gland treatment withing 1 month of enrollment?
- Having any conditions or are in a situation, which in the investigator's opinion, may put the subject at significant risk, may confound the study results, or may significantly interfere with their participation in the...
- Currently pregnant or breast feeding
The study team makes the final eligibility decision.
Where it is enrolling
- Pittsburg, Kansas, United States
- Kansas City, Missouri, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Pittsburg, Kansas, United States; Kansas City, Missouri, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.