Diabetes Mellitus, Type 1 study: Tirzepatide vs Acetaminophen
Official title A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity
ClinicalTrials.gov ID: NCT07803744
What this study is testing
What is Tirzepatide?
An investigational once‑weekly injectable medicine being studied for type 1 diabetes mellitus and overweight or obesity.
Also referred to as LY3298176.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to learn how tirzepatide changes how quickly the stomach empties food in people with type 1 diabetes and excess weight.
- Who it's for
- Adults who have type 1 diabetes and are overweight or obese.
- What's involved
- Participants will receive tirzepatide and attend scheduled visits for medical tests and monitoring.
- Time commitment
- The study lasts about 8 weeks, including screening and follow‑up visits.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Have a diagnosis of type 1 diabetes mellitus (T1DM) and have been treated with insulin for at least 1 year prior to screening
- Have a body mass index (BMI) greater than or equal to 25.0 kilograms per square meter (kg/m2) at screening
- Are of stable weight, that is a self-reported change of 5 kg or less, for at least 90 days prior to screening
You likely can't join if
- Participants who have a known clinically significant gastric emptying abnormality
- Have undergone weight loss surgery such as gastric bypass (bariatric) surgery or restrictive bariatric surgery
- Have known allergies or intolerance to acetaminophen, tirzepatide, or glucagon-like peptide-1 (GLP-1) receptor agonists
The study team makes the final eligibility decision.
Where it is enrolling
- Miami, Florida, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Miami, Florida, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.