Clinical trial for Kidney Cancers
Official title Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALA
ClinicalTrials.gov ID: NCT07828704
What this study is testing
What is 5-Aminolevulinic acid Hydrochloride (Gliolan®)?
an investigational oral drug being studied to help visualize kidney cancer during surgery is designed to accumulate in tumor cells and emit fluorescence when exposed to blue light
Also referred to as Gleolan, 5-ALA.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether a drug called Gleolan is safe to use. It also checks if this drug helps doctors see the cancer better during surgery.
- Who it's for
- You may be able to join if you have suspected kidney cancer and need a partial kidney removal.
- What's involved
- You would take Gleolan before your surgery. During the operation, doctors will use a special light to look at your kidney.
- Time commitment
- The study lasts from before your surgery until your follow-up visits after the operation.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Patients aged 18 or older
- Has indications for standard-of-care partial nephrectomy
- Able to provide informed consent
- Able to comply with study requirements
You likely can't join if
- Known porphyria or hypersensitivity to porphyrins
- Pregnant or breastfeeding women
- AST or ALT \> 2x upper limit of normal within 30 days prior to surgery
- Participation in another investigational study within 30 days
- Known allergy or contraindication to 5-ALA or its components
The study team makes the final eligibility decision.
Where it is enrolling
- Detroit, Michigan, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Detroit, Michigan, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.