Clinical trial for Obsessive - Compulsive Disorder
Official title Clinical and Biological Correlates of Obsessive-Compulsive Disorder and Online Mindfulness-Based Cognitive Therapy
ClinicalTrials.gov ID: NCT07834567
What this study is testing
- What it's testing
- This study checks if a specific online mindfulness therapy is practical for people with OCD. It also looks at how body markers relate to symptom severity and treatment results.
- Who it's for
- The study is looking for adults with a diagnosis of OCD, as well as healthy people for comparison.
- What's involved
- Participants will join live online group therapy sessions. Some participants will also provide blood and saliva samples for testing.
- Time commitment
- The study involves attending group therapy sessions and providing biological samples, but the total duration is not specified.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45
You may be able to join if
- Patients with OCD.
- Diagnosis of obsessive-compulsive disorder (OCD) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
- Age between 18 and 45 years
- Stable pharmacological treatment for at least 3 months prior to the start of the experimental intervention
- No previous experience with mindfulness meditation, or previous mindfulness meditation experience with no practice during the 12 months prior to...
You likely can't join if
- Diagnosis of schizophrenia spectrum or other psychotic disorders, including schizoaffective disorder
- Diagnosis of bipolar and related disorders
- Major depressive disorder in an acute phase
- Active substance use disorder or alcohol use disorder as the primary diagnosis
- Personality disorders of clinically significant severity
- Documented major neurocognitive disorder. Neurological conditions or medical conditions with a clinically significant impact on cognitive or mental...
See the full eligibility criteria
- Patients with OCD.
- Diagnosis of obsessive-compulsive disorder (OCD) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
- Age between 18 and 45 years
- Stable pharmacological treatment for at least 3 months prior to the start of the experimental intervention
- No previous experience with mindfulness meditation, or previous mindfulness meditation experience with no practice during the 12 months prior to study enrollment
- Ability and willingness to provide written informed consent.
- Diagnosis of schizophrenia spectrum or other psychotic disorders, including schizoaffective disorder
- Diagnosis of bipolar and related disorders
- Major depressive disorder in an acute phase
- Active substance use disorder or alcohol use disorder as the primary diagnosis
- Personality disorders of clinically significant severity
- Documented major neurocognitive disorder. Neurological conditions or medical conditions with a clinically significant impact on cognitive or mental functioning
- Previous mindfulness meditation practice within the 12 months prior to study enrollment
- Age between 18 and 45 years, with age matching within a maximum difference of ±3 years from the corresponding index patient. In all cases, control participants must be at least 18 years and no older than 48 years
- Voluntary participation in the study.
- Age younger than 18 years
- History of psychiatric disorders, as assessed using the Structured Clinical Interview for DSM-5 Disorders - Clinician Version (SCID-CV)
- Intellectual developmental disorder.
- Current substance use disorder or alcohol use disorder
- Neurological disorders, including Parkinson's disease, major neurocognitive disorders, neurodegenerative syndromes, ataxias, multiple sclerosis, cerebrovascular events (stroke or transient ischemic attack [TIA])...
- Systemic medical conditions (e.g., diabetes mellitus, atherosclerosis, chronic arterial hypertension, or malignancies) requiring pharmacological treatment
- Current or previous mindfulness meditation practice within the 12 months prior to study enrollment
The study team makes the final eligibility decision.
Where it is enrolling
- Brescia, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 45 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Brescia, Italy. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.