Atherosclerosis study: VERVE-102
Official title A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
ClinicalTrials.gov ID: NCT07839936
What this study is testing
What is VERVE-102?
VERVE-102 is an investigational medicine, given as an IV infusion (through a vein), being studied as a potential treatment for atherosclerosis.
Also referred to as LY4636581.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to measure the change in bad cholesterol (LDL-C) with VERVE-102 compared to placebo in adults who have plaque buildup in their arteries or are at high risk of developing it.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Established atherosclerotic cardiovascular disease (ASCVD) and/or at a high risk of ASCVD
You likely can't join if
- History of confirmed or suspected homozygous familial hypercholesterolemia (HoFH)
- Chronic liver disease
- Current treatment with PCSK9 inhibitor or prior treatment within specified timeframe
The study team makes the final eligibility decision.
Where it is enrolling
- DeSoto, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at DeSoto, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.