Obesity or Overweight study: Petrelintide
Official title A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes
ClinicalTrials.gov ID: NCT07843485
What this study is testing
What is Petrelintide?
Petrelintide is an investigational once‑daily injectable medicine being studied for weight management in people with overweight or obesity and type 2 diabetes.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether petrelintide can help you lose weight when combined with a lower‑calorie diet and more exercise. It also looks at how safe the drug is.
- Who it's for
- You may be able to join if you have type 2 diabetes and are overweight or obese.
- What's involved
- You will take petrelintide or a pretend treatment, follow a diet plan, and exercise more. You will have regular check‑ins and give blood samples.
- Time commitment
- The study lasts about 12 months and includes several clinic visits and phone check‑ins.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Participants with BMI ≥ 27 kg/m²
- T2D diagnosis as per World Health Organization (WHO) classification (or other locally applicable standards) with HbA1c ≥ 6.5% to ≤ 10% (48-86...
- Stable treatment with either diet and exercise alone, basal insulin, or selected oral glucose-lowering agents, for at least 90 days prior to and...
- History of at least one self-reported unsuccessful dietary effort to lose body weight
You likely can't join if
- History or presence of proliferative diabetic retinopathy, or diabetic macular edema
- Current or previous treatment with petrelintide or any other amylin analog
The study team makes the final eligibility decision.
Where it is enrolling
- Los Angeles, California, United States
- Manassas, Virginia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Los Angeles, California, United States; Manassas, Virginia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.