Clinical trial for Prostate Cancer
Official title Tractography-Guided Nerve-Sparing in Prostate Cancer
ClinicalTrials.gov ID: NCT07847385
What this study is testing
- What it's testing
- The study will use diffusion tensor MRI and 3‑D reconstruction to map the nerves around the prostate before surgery and again six months after. It will compare the two maps to see how surgery changes the nerves and whether those changes relate to erectile and urinary function.
- Who it's for
- Men who are scheduled to have a radical prostatectomy for prostate cancer.
- What's involved
- Participants will have an MRI scan before surgery and another six months after. The scans will be turned into 3‑D nerve maps that the surgeon can view during the operation. After surgery, the new maps will be compared to the pre‑surgery maps and participants will complete questionnaires about erectile and urinary function.
- Time commitment
- The study lasts about six months, with two MRI visits (pre‑surgery and six months post‑surgery) and completion of questionnaires at the six‑month follow‑up.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, men only
You may be able to join if
- Histological confirmed diagnosis of prostate cancer (PCa) based on prostate biopsy
- Multidisciplinary indication for radical prostatectomy, validated by the Urology Tumor Board
- No prior treatment of prostate cancer
- Capacity to provide informed consent
You likely can't join if
- Unwillingness to participate.
- Pre-existing impaired sexual function before surgery (IIEF5 Score of ≤21)
- Diagnosis of neuropathy
- Inability to comply with study procedure (e.g. due to language barriers, psychological disorders, dementia, anxiety/claustrophobia during pelvic MRI...
The study team makes the final eligibility decision.
Where it is enrolling
- Geneva, Canton of Geneva, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Geneva, Canton of Geneva, Switzerland. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.