Recruiting at 1 site Phase 4 Acne Vulgaris

Trial comparing treatments for Acne Vulgaris

Official title Comparing Nadifloxacin Plus Tretinoin Versus Clindamycin Plus Tretinoin Creams for Mild-to-Moderate Acne

ClinicalTrials.gov ID: NCT07915648

What this study is testing

What is nadifloxacin?

nadifloxacin is an investigational medicine, applied to the skin once daily, being studied as a potential treatment for acne vulgaris.

Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The purpose of this randomized controlled trial is to compare the effectiveness of two topical combination treatments for mild-to-moderate acne vulgaris: 1% nadifloxacin with 0.025% tretinoin cream versus 1% clindamycin with 0.025% tretinoin cream. The study will be conducted in the Department of Dermatology, Nishtar Hospital, Multan, and will enroll adults aged 18 to 40 years of either gender who are newly diagnosed with mild-to-moderate acne vulgaris.
  • Phase 4: studies an already-approved treatment
  • Which group you join is decided by chance.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 40

You may be able to join if

  • newly diagnosed with acne vulgaris
  • mild to moderate severity

You likely can't join if

  • Drug induced acne or acneiform eruptions (corticosteroids, antiepileptics, lithium, iodides)
  • endocrine disorders (PCOS, Cushing syndrome, congenital adrenal hyperplasia)
  • chronic dermatological conditions affecting face (Rosacea, seborrheic dermatitis, perioral dermatitis)
  • pregnant or lactating women
  • chronic systemic illness (chronic liver disease, kidney disease)
  • patients with known hypersensitivity to study medications

The study team makes the final eligibility decision.

Where it is enrolling

  • Multan, Punjab Province, Pakistan

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 40 years. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Multan, Punjab Province, Pakistan. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.